COVID-19 Research, Drug trials and Pathophysiology

Discussion in 'Coronavirus (COVID-19) News' started by Bowerbird, Apr 13, 2020.

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  1. LafayetteBis

    LafayetteBis Well-Known Member Past Donor

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    COVID-19 DEATHS PER CAPITA - US & EU

    I have made it a point here that the death-rates are not being quoted in a comparative manner. That is, it is unacceptable that the deaths-per-capita between the US and EU, both comparative entities, not be reported. Both entities are "states" in their own right.

    So, I went about to find the deaths-per-capita (of population) "per national state" and have come up with the following:
    US - 418
    EU - 263

    And I will mention yet again that the significant difference between the two is "leadership". The EU had far more preparedness to undertake national-leadership that coordinates the means necessary to care for the sick than exists still today in the US. (Btw, that occurred because the two in charge of both the EU and primary-state Germany are females!)

    For the sake of Uncle Sam, I hope this does not happen again in the future.

    Uncle Sam is TOTALLY PREPARED to retaliate in case of a military invasion but totally unprepared for an invasion of a viral nature.

    Shame on you, Uncle Sam ... !
     
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  2. AmericanNationalist

    AmericanNationalist Well-Known Member

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    Actually, the EU is more of a centralized country, whereas Trump had a mixed response. He tried to centralize the response at first, got push back from the States then he basically put the whole plate on the States and proceeded not to give a damn.

    The best case would have been States and the federal government working together, and that takes both sides and neither side wants to actually "lose face" at this point.

    The only benefit to Biden might be, it would be a reset for the Congresspersons and State governors to 'work' with the political puppet in Biden, there's no real value in opposing Biden as he's politically useless. He's there to rubber stamp everything.
     
  3. LafayetteBis

    LafayetteBis Well-Known Member Past Donor

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    HAS AMERICA LEARNED ITS VIRUS-LESSON?

    When people are dying such "antics" are irresponsible. The state-Federal coordination is not beyond the ability of a PotUS (and it is clearly his/her responsibility). I, for one, am sure that had Hillary become PotUS she would have reacted very, very quickly.

    Both the states and governments have got to learn how to get-along, prioritize and act. Above all act quickly because this virus spreads with amazing ease person-to-person. Let's hope we have learned that lesson - at a sorrowful price - for good! A future repeat is highly probable.

    And a repeat IS going to happen. This virus, unlike the last one in the early 1900s, is not going away.

    The world has far too many people and such viruses traverse the planet like a wildfire due to high population densities. Next time this happens - and there WILL BE a next time - the human travel lock-down must be immediate and sustainable. (We must prepare for it. That is, act immediately and have the rudimentary ability to take care of those stricken.)

    I do hope we'e learned OUR lesson regarding how deadly these viruses are ...
     
    Last edited: Jul 15, 2020
  4. Well Bonded

    Well Bonded Well-Known Member Past Donor

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    It was tried at the Federal level and the states pushed back as they understood a one size fits all solution is irresponsible and a overstepping of power by the Federal Government.

    Oh yes for sure just like she did at the Benghazi attack. Hillary is a political jerk of the first class and incapable of making critical decisions.
     
    Last edited: Jul 15, 2020
  5. kreo

    kreo Well-Known Member

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    Death rate in EU is higher.
    https://www.ecdc.europa.eu/en/covid-19-pandemic
     
  6. LafayetteBis

    LafayetteBis Well-Known Member Past Donor

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    Last edited: Jul 15, 2020
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  7. kreo

    kreo Well-Known Member

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    John Hopkins is reputable source
    https://coronavirus.jhu.edu/data/mortality
     
  8. LafayetteBis

    LafayetteBis Well-Known Member Past Donor

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    Of course it is - but that is not the point.

    Your arithmetic is correct - but it is the wrong value that you are citing. You are citing the total number of deaths over a short period of time (a day, a week), when what matters in such a circumstance is accumulated deaths per total population.

    The number of deaths per period-of-time is good for understanding the progression of the viral-infection. But the impact upon a nation of people is better appreciated by deaths-per-population ...
     
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  9. HumbledPi

    HumbledPi Well-Known Member

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    About testing and tracing. Tracing may have worked in the beginning of this pandemic if we has seized on the opportunity to do that, that's no longer possible. It's simply out of the realm of mathematics to believe we can still test and trace in order to contain this pandemic. That ship has sailed, we missed that chance. Mass testing and tracing does not work at this stage of the pandemic, it only worked in the very early stages in South East Asia.

    In some cases, scientists could tell whether some animals and some people just had the virus in their throat but not yet replicating in the body -- because most tests can't tell whether it is a full 'alive' virus or if they are pieces of 'dead' virus. Also, there are stages in which the virus cannot be detected even if you have it in the early stages. The only thing a test will tell is that a person is 'positive' but that person won't know how long they will have to isolate. Just knowing the numbers of tests being done is worthless information.

    Some people will test negative when in fact that have the virus, it's just not detectable yet. And about tracing, we can't properly and effectively trace 60,000 new people per day. Tracing will only work once the 15 min test is available to everyone, which it isn't. If there are 60k people that are confirmed have it, there would be at least another 60,000 who have it without symptoms, and they cannot be traced anyway. Asymptomatic spread is where contact tracing becomes untenable. Even with testing every two weeks and a 24-hour lag in results, universal testing would catch less than half of asymptomatic carriers during their most infectious period.

    Abortion
    I haven't read every post in this thread and don't know how or where it evolved into a discussion about abortion but I just want to add a point. Covid-19 has been around in the US since the first case was detected and confirmed in January. We're six months into this pandemic and all hell has broken loose, as the saying goes, for new infections. Let's assume that there have been cases where a woman is infected while pregnant. Perhaps it has already happened, perhaps it will happen in the near future. The point is, right now, there is no scientist on earth than can predict how the virus will affect the fetus of a woman carrying Covid-19.

    What happens if in 3 or 6 months, women start giving birth to infants that will have suffered some horrible consequence from her carrying the virus during gestation? I can only think back to the 60's in Great Britain when women were giving birth to babies with severe physical deformities, missing limbs etc. The common denominator was a drug prescribed to treat morning sickness in pregnant women. Morning sickness usually occurs during the first trimester, the time when the fetus is forming. The drug was Thalidomide and once pinpointed as the cause of these infants born with missing limbs, it was quickly taken off the market and many abortions performed on women who had been taking the drug.

    The case of American school teacher Sherri Finkbine was in the national news because she had been taking Thalidomide and learned she was carrying a fetus that would be severely deformed and likely die. She had to leave the country for an abortion in Sweden.
     
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  10. kreo

    kreo Well-Known Member

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    Year over year moving average does not deviate from normal.
    There is absolutely nothing that tells us about "disaster".
     
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  11. SEAL Team V

    SEAL Team V Banned

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    Not to hijack the thread or anything, but drug trials is in the thread title so


    [​IMG]
    Could cannabis be a possible treatment for COVID-19?
    Natacha Larnaud

    10 hrs ago

    Holy crap, now it’s time to invest in that weed stock.
    Top Marijuana Stocks for July 2020
    HARV.CX, VLNS.TO, SII.TO are top for value, growth, momentum respectively

    Experts from the University of Nebraska and the Texas Biomedical Research Institute are recommending that scientists look into how the potential use of cannabis-derived CBD might help treat dangerous lung inflammation from the novel coronavirus. They said its anti-inflammatory properties make it a likely candidate to treat some of the more dangerous symptoms of the coronavirus.

    There is no scientific evidence that cannabis or its compounds can help with COVID-19 specifically, but in a new peer-reviewed articlein Brain, Behavior, and Immunity, researchers explained that "recent reports have suggested that acute infection is associated with a cytokine superstorm, which contributes to the symptoms of fever, cough, muscle pain," and in severe cases, pneumonia.
    Like stoners really need another excuse to smoke a joint.
     
    Last edited: Jul 18, 2020
  12. AmericanNationalist

    AmericanNationalist Well-Known Member

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    Then there's the liquid counterpart, which actually has the full CBD. I'd never been so delirious as when my brother spiked my drink the other day lol. And I do have to admit, for that portion of the day my asthma was absolutely gone but so was my sanity lol.
     
  13. Well Bonded

    Well Bonded Well-Known Member Past Donor

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    What the article is referring to is CBD not THC.

    THC is what gets people high, CBD is more of a pain medication, THC bearing leaves are not legal at the federal level yet, CBD is.
     
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  14. Bowerbird

    Bowerbird Well-Known Member

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  15. LangleyMan

    LangleyMan Well-Known Member

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    Republican states "pushed back," and a President who encouraged workers to push for reopening can hardly claim he made an effort to coordinate a federal response.

    Something is wrong with this...

    F1EA55B1-32DF-419B-9CCB-91647B18A20F.jpeg

    It reminds me of the old saying that a fish rots from the head.
    Many of the other countries in the graph above used different approaches in different parts of their countries as part of a national strategy. British Columbia (5m people) was opening its economy in early May because it has these numbers...

    E1861F20-A33D-4F6F-97A7-A347B24907B7.jpeg

    ... while Quebec and Ontario were still clamping down.
     
  16. LangleyMan

    LangleyMan Well-Known Member

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    Compare the death rate in this country with Canada death that's as urbanized as this country. They're at 24.09/100K while we're at 44.07/100K.
     
  17. kreo

    kreo Well-Known Member

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    They are not politicized as US. They have no goal to overturn Trump, so they report more ore less true data. In US, most of the data is fake.
    Since in Canada and European countries health care access is universal medical facilities do not care about profit, so they have not reason to overreport cases.
    Another reason is election, Democrat party members are trying to inflate number of cases in order to blame Trump.
    If relative numbers of deaths in US and Canada are similar but number of cases in US is ten times greater then it is obvious that something is wrong with counting.
     
    Last edited: Jul 26, 2020
  18. LangleyMan

    LangleyMan Well-Known Member

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    Wrong. If we get that number of new cases down, we can then test and trace new cases to cut off lines of transmission.
    It's working now in Canada, Australia, and many European countries. The formula is straightforward: use the like of shutting down types of businesses and stay-at-home orders to get the number of new cases down, then go at testing and tracing.
    Right, we can't trace 60,000 new cases, but we could trace a smaller number like they have in British Columbia (5m people) where a test comes back in one day.

    6C893913-2AA5-4156-AE2A-7B829AF1E1BD.jpeg
     
    Last edited: Jul 26, 2020
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  19. LangleyMan

    LangleyMan Well-Known Member

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    It's CBD (no wowie from CBD!) that might help and is available in stores.
     
    Last edited: Jul 26, 2020
  20. LangleyMan

    LangleyMan Well-Known Member

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    Uh huh--there's a vast conspiracy of doctors to misreport COVID-19 cases. Many of the dead people we count aren't actually dead. :rolleyes:
    Ah, so most doctors are Democrats.

    https://www.beckershospitalreview.com/hospital-physician-relationships/physicians-in-these-14-specialties-more-likely-to-vote-republican.html

    Why aren't Republican doctors exposing this alleged fraud?
    Part of the reason the death count is higher per reported case in Canada is they killed a lot of seniors in skilled nursing facilities because of the way those facilities were run. At one point it was so bad in Ontario and Quebec that they sent in the army to look after patients.
     
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  21. kreo

    kreo Well-Known Member

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    Yes, even though overwhelming majority of doctors are republicans, due to lock-down they have less patients (i.e less income). In order to increase revenue they report more COVID-19 cases.
    The number of cases in US is ridiculously high, there is no mathematical model that can explain that surge.
     
  22. LangleyMan

    LangleyMan Well-Known Member

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    Good to know Republican doctors are crooks.
    Sure, there is.
     
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  23. CenterField

    CenterField Well-Known Member Past Donor

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    In the past the overwhelming majority of doctors were Republicans. I believe that it is no longer the case. But what makes you think that reporting more COVID-19 cases increases a doctor's revenue? The payments are for treatments and procedures, not for reporting cases. These patients have been needing the treatments and procedures, and there is no evidence of fraud. This is a long article about it but very informative and interesting, if you want to read it all:

    https://www.factcheck.org/2020/04/hospital-payments-and-the-covid-19-death-count/

    Another strange misconception is that the CDC is interested in inflating the case count. The CDC is directed by a Trump loyalist, personally nominated by Trump. Why would he have an interest in over-counting cases?

    An indirect way to look at the real impact in deaths, is to look at the "deaths by all causes" number. This is a very reliable number, because in our country, virtually everybody who dies gets counted, except if a serial killer manages to kidnap and kill someone and buries the victim in his backyard, haha. So, what do we see? A huge spike in deaths by all causes, from 80% increase in calmer areas, to 300% increase in hot spots, as compared to similar periods in years past, which shows that people are indeed dying in this pandemic, in high numbers.

    The number of cases in the US are not ridiculously high. So far, the number of confirmed cases for this highly infectious disease, is 1.31% of our total population. Rather than "no mathematical model can explain" this number, I'd say it's actually a surprisingly modest number, because we are dealing with a coronavirus, a family of viruses notorious for getting to most of the population. Other coronaviruses are important members of the viruses responsible for common colds. Think of it: in average, each American gets the common cold 5 times per year. That is, these viruses go everywhere and get everybody.

    Think of the flu: about 8% of our population gets sick from it every year. Well, we do have a vaccine for the flu and 50% of our people get it; in certain years it protects a lot, in certain others not as much, but even in weak vaccine years, it does decrease the number of cases., so without a vaccine we might expect up to twice as many case, or some 15% of the population. OK, the SARS-CoV-2 is at least sort of twice as infectious as the flu if not 4 times more, with a R0 number (the number that measures infectiousness) calculated anywhere between 2.0 and 5.7, while the flu's is 1.3.

    So, say that the SARS-CoV-2 is in average three times more infectious than the influenza virus, and as you know there's no vaccine yet, so we should expect 45% of the population to get it when it's all said and done.

    So, we have 1.31% of the population with confirmed cases (maybe ten times as many undiagnosed cases which would put us at 13%) and you are surprised? I don't see why you should be.
     
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  24. kreo

    kreo Well-Known Member

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    I see different CDC table.
    It shows that excess deaths goes down since the begining of June
    I am not sure which table you are referring to.but I see that
    In June 6, it was 108 i.e. 8% excess and then
    105, 103, 101, 97, 87, 51

    https://www.cdc.gov/nchs/nvss/vsrr/COVID19/index.htm


    Your article is saying there is no evidence of fraud.
    I am sure there is absolutely no fraud, because there is no standards or criteria for fraud. so they do not have to prove anything. Just report a suspicion.
     
    Last edited: Jul 26, 2020
  25. CenterField

    CenterField Well-Known Member Past Donor

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