New Details Emerge About Coronavirus Research at Chinese Lab

The virus was manipulated to increase transmissibility. That's Gain of Function.

How that is not "Gain of Function" is just *******s like Fauci trying to play word games.

 

The WIV1 backbone they used already coded for spike proteins (they mention that the new spike sequences were 99% similar to the WIV1 spikes). They just replaced them with the discovered viruses' spikes to test whether the discovered spikes were infectious or not. That's not gain of function research (as defined in the Paul/Fauci exchange) for two reasons: 1) the existing WIV1 virus was already infectious and 2) whether the new spikes were infectious or not was unknown so there was no intentionality to make the WIV1 virus more infectious.

 

And you can quote the part of the research that says that, yes?

 

That's not what the paper said. Sorry. You may be referring to some other paper.

 

That's literally what this means, from the study:

I'm honestly starting to think that all of this is just the result of folks not being able to understand a research study paper.

 

To you no, to everyone else they can listen to Rand Paul read the report and Fauci agree with it. Then he reads Fauci's own published definition that matches exactly what the grant app says. Somewhere you loose attention, to everyone one else not a lefty they hear exactly Fauci's definition.

 

"We constructed a group of infections bacterial artificial chromosome clones with a backbone of WIV1...."
The "backbone" of the WIV1 is not what makes it contageous. Good grief. Maybe you're the one that doesn't understand the research....


From that section:
In the current study, we successfully cultured an additional novel SARSr-CoV Rs4874 from a single fecal sample using an optimized protocol and Vero E6 cells [17]. Its S protein shared 99.9% aa sequence identity with that of previously isolated WIV16 and it was identical to WIV16 in RBD. Using the reverse genetics technique we previously developed for WIV1 [23], we constructed a group of infectious bacterial artificial chromosome (BAC) clones with the backbone of WIV1 and variants of S genes from 8 different bat SARSr-CoVs. Only the infectious clones for Rs4231 and Rs7327 led to cytopathic effects in Vero E6 cells after transfection (S7 Fig). The other six strains with deletions in the RBD region, Rf4075, Rs4081, Rs4085, Rs4235, As6526 and Rp3 (S1 Fig) failed to be rescued, as no cytopathic effects was observed and viral replication cannot be detected by immunofluorescence assay in Vero E6 cells (S7 Fig). In contrast, when Vero E6 cells were respectively infected with the two successfully rescued chimeric SARSr-CoVs, WIV1-Rs4231S and WIV1-Rs7327S, and the newly isolated Rs4874, efficient virus replication was detected in all infections (Fig 7). To assess whether the three novel SARSr-CoVs can use human ACE2 as a cellular entry receptor, we conducted virus infectivity studies using HeLa cells with or without the expression of human ACE2. All viruses replicated efficiently in the human ACE2-expressing cells. The results were further confirmed by quantification of viral RNA using real-time RT-PCR (Fig 8).

 

Yes, Trump deserves to be behind bars. Remember, your position is that you are not a Trump fanboy.

 

If Trump's found guilty of a crime, then sure prosecute him to the fullest extent of the law. The issue here is a reauthorization of a grant that was denied, TWICE. Something fishy went down in Washington from 2017-2020 surrounding this aid, and we need to find out what.

 

It all ends up at the top, Trump. Corruption and Trump are pretty well the same.

 

Simple? I don't think so. Obesity is a far more complex problem. It sounds simple. But the social engineering required to solve the obesity problem is far more complex than the problem of engineering a virus that can target a specific protein.

 

I ask for quotes because it's easier to parse language and see where the error is. The research report doesn't describe gain of function research, as either Fauci or Paul define it during that exchange. If you disagree, feel free to post quotes so we can parse the language. I've watched that clip several times just today and quoted the research multiple times in this thread. It's not gain of function research as defined by Paul/Fauci.

 

I didn't say it was? This seems like it might be a Ship of Theseus type of issue causing a misunderstanding.

Right, they confirmed that the newly discovered spikes were infectious. So were they more infectious than the original WIV1 that was used as the backbone? Were they intending to make something more infectious than WIV1, or were they just testing the infectivity of the new spike proteins?

 

You argue that it's not gain of function because: A: The source material was already infectous and B: Even so, there wasn't intention on their part. Well, would the source material have merged with the 8 strands they chose under normal circumstances?(ie: outside of the petrie dish). I doubt it, because if so they would've found what they created outside of the lab. So even though the source material could have affected humans, we don't know if it could have merged with the test subject without human interference.

So was there 'intention'? We'll never know. I'm not them. I can't say what their intentions were. We can say as a result of their actions, they created a test subject in the lab that otherwise didn't exist before the experiment, and thus they intended to see what this would bring about.

 

The original had spike proteins that were very similar to the ones they discovered. If you want to just say that creating something new qualifies as "gain of function" you're going to shut down a whole bunch of research into medicines and food in the US. There's a reason Paul and Fauci were trying to be specific about what the term meant.

The intentions described in the paper were to test whether eight new, naturally occurring spike protein sequences were infectious. The research was supposed to help discover if there were any SARS-CoV-1-like viruses likely to come out of Wuhan any time soon.

 

I see reading papers isn't your specialty. The WIV1 backbone wasn't infectious at all to humans.

 

I don't know whether or not Dr. Fauci broke the law. What I do know is that all government agencies are run through our EXECUTIVE branch of government. That is one of the main reasons that we NEED a Chief Executive, a.k.a., a President. And so, ultimately, for anything that occurs in any U.S. agency-- whether it is NIAID, NIH, HUD, or the V.A.-- the buck stops with the President (which is why it is important that he insures these agencies have the best people, running them). So if something happened that should not have, under Trump's watch, then that (holding Trump responsible) very much is, "how this works."

 

Gain of Function was banned, against the law. You can't keep people from breaking the law. I for one don't want Biden nor Trump's nose deep in any of those departments, we have oversight and now is the time to punish offenders. I guess if everything is the President's fault then everyone not vaccinated is Biden's fault, the Delta variant surging in America is Biden's fault, the deaths are higher than they were a year ago and those are on Biden as well. As you say the BUCK stops with Biden and if he doesn't fire and prosecute Fauci's lying ass then that's on him as well.

 

What does a lab studying Coronavirus in the city where it first occurred, have to do with a pandemic? China said it came from bats nearby. And the MSM corroborated it. Why would they lie? /derp

China should be held liable for war crimes against the planet. And Fauci should be disgraced for lying as well. You know who should be thanked? Trump. Because he’s the only leader man enough to just state the obvious. The rest pussyfooted around because they were too chicken$&@.

 

well, looks like they posted a link you would be interested in then.

 

How do you hold someone who's not in office responsible for a decision that was made in the shadow of his administration? If, for example, a federal agent shoots a women in the face on the steps of Congress do we toss the president in jail? Which one? The one that hired him, the one that he acted under? Both?

 

It's just a sheer happenstance that a deadly plague breaks out in the same area as a lab investigating what happens when you take spike proteins and splice them into Coronaviruses to make them more infectious to humans.

Sheer freaking happenstance. Kinda like last week, when I successfully guessed three Powerball lottos in the same day.

 

Says the people who, instead of wearing masks, are literally self-medicating with livestock products designed for sheep.

 

You do understand it’s been a medication for humans for decades, right? Not saying it works for Covid, but it should be researched like any potential treatment.

 

No no, these people I'm speaking of aren't going to doctors, developing a treatment plan, obtaining a prescription for a human product filled by a licensed pharmacist, and following the directions for dosage and frequency. These people are going to Rural King and buying off the shelf livestock products and consulting their QAnon facebook groups on how to self-medicate.